直肠癌根治术后硬膜外镇痛效果的临床观察

Clinical observation of the effectiveness of patient controlled epidural analgesia after radical resection of rectal carcinoma

目的：观察患者自控镇痛对直肠癌术后镇痛的效果和患者恢复的影响.方法：选择ASAⅠ～Ⅱ级直肠癌根治手术患者160例,随机分为自控镇痛（PCEA组）和非自控镇痛（PMA组）各80例,观察两组术后镇痛的效果. 结果：自控镇痛术后6～24h镇痛效果的有效率与对照组（非自控镇痛）比较有显著性差异（P＜0.05,P＜0.01）;患者术后心率、血压6h、12h与PMA组比较有差异,肠蠕动恢复时间及下床活动时间与对照组比较无显著性差异（P＞0.05）.结论：自控镇痛用于直肠癌术后镇痛效果好,术后恢复快,使用安全.

Objective：To study the effectiveness of patient controlled epidural analgesia（PCEA） for post-operative pain relief after radical resection of rectal carcinoma. Methods ：A total of 160 patients who undergoing radical resection of rectal carcinoma were randomly divided into two groups：the PCEA group （group A,n=80） and the control group （group B,n=80） ,and the effectiveness of pain relief of these two groups were compared after operation. Results ：The quality of pain relief in the PCEA group was obviously superior to that of the control group（P〈0. 05,P〈0.01）. There was significant difference between these two groups by comparing the post-operative heart rate, blood pressure,at 6 and 12 hours. No difference of Bowel movement and activity time was found （P〉0.05）. Conclusion： After radical resection of rectal carcinoma,PCEA could effectively relieve pain by providing faster recovery and high safety to the patient.