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RNA干扰及其在肿瘤研究中的应用进展 被引量:1

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摘要 双链RNA(double-Stranded RNA,dsRNA)能特异性地抑制基因的功能,使内源性mRNA降解,导致基因沉默,这种现象称为RNA干扰(RNA interference,RNAi)。与其它传统的方法相比,小干扰RNA(Small interfering RNAs,or short interference RNAs,siRNAS)具有更好的抑制效果。RNAi的应用为研究肿瘤的基因功能提供了新的方法,并可能用于基因的特异治疗。
作者 蒲丹 李为民
出处 《国际呼吸杂志》 2006年第10期738-741,745,共5页 International Journal of Respiration
基金 国家自然科学基金项目(30270587) 教育部博士点基金(20050610056)
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