2000～2005年长江流域6城市碳青霉烯类抗生素应用分析

Analysis of carbopenem antibiotics used in six cities in the Yangtze areas during the period of 2000～2005

目的评估长江流域6大城市碳青霉烯类抗生素的临床应用状况。方法主要采用金额分析法对2000～2005年长江流域6大城市样本医院碳青霉烯类抗生素的消耗数据进行分析。结果6年间碳青霉烯类抗生素消耗数据每年分别增长25％，38％，29％，12％和26％；6个城市中上海占总消耗量的48％，杭州21％，南京8％，武汉8％，成都9％，重庆6％；其中亚胺培南占总量的82％，6年间增长了2．07倍，帕尼培南增长398倍，美罗培南1760倍。结论长江流域碳青霉烯类抗生素的用量快速、稳定增长，值得关注。

OBJECTIVE To find out the situation of carbopenem antibiotics used in six cities in Yangtze areas. METHODS The data of consumption for carbopenems used in six cities in the Yangtze areas during the period of 2000～2005 were analyzed by using analysis method of sum of charges for drugs. RESULTS In the last 6 years, the growth of carbopenems used in Yangtze areas was respectively 25%, 38%, 29%, 12% and 26% every year. The ratio of consumption was 48% （Shanghai）, 21% （Hangzhou）, 8% （Nanjing）, 8% （Wuhan）, 9% （Chenduo）, 6% （Chongqin） among the six cities in Yangtze areas. Imipenem has 82% in carbopenems used. CONCLUSION The amount of consumption has steadily increased for carbopenems in Yangtze areas. It should be paid close attention in clinical use in future.