核素骨显像在71例骨外恶性淋巴瘤的临床应用

The clinical application of nuclide bone imaging in malignant lymphomas

目的探讨核素骨显像在恶性淋巴瘤骨浸润中的临床应用价值。方法收集经病理证实的71例恶性淋巴瘤骨显像患者病例,其中霍奇金淋巴瘤(HL)8例,非霍奇金淋巴瘤(NHL)63例。经静脉注射99mTc-垭甲基二膦酸盐(99mTc-MDP)555-925 MBq后2．5-6h行全身骨显像检查。结果骨浸润病变者31例,其中8例HL中骨浸润3例,63例NHL中骨浸润28例。总病灶数103个,除2个骨放射性缺损外,101个浓聚灶分别为:脊柱35个(34．65％)、四肢骨及关节30个(29．70％)、肋骨14个(13．86％)、骨盆13个(12．87％)、颅骨5个(4．95％)及胸骨4个(3．96％)。结论核素骨显像在恶性淋巴瘤骨浸润的临床分期、治疗监测和预后转归等方面具有较高的临床价值。

Objective To evaluate the clinical application value of nuclide bone imaging in malignant lymphoma. Methods 71 cases of patients were diagnosed by pathology as malignant lymphoma, among whom there were 8 cases of Hodgkin disease（HL） and 63 cases of non-Hodgkin disease （NHL）. The examinations were performed from 2.5 to 6 hours later after the intravenous injection of ^99mTc-MDP （555 - 925MBq）. Results 31 cases were bone-infiltrating lesions, including 3 cases of HL and 28 cases of NHL The total number of the focus was 103, except 2 cases of bone lack, including 35 foci in vertebral column （34.65%）, 30 foci in limb and joint （29.70%）, 14 foci in rib （13.86%）, 13 foci in elvis （12.9%）, 5 foci in skull （4.95%） and 4 foci in sternum （3.96%）. Conclusion The nuclide bone imaging has a high value in the clinical stage, therapeutic observation and prognosis of bone-infiltrating malignant lymphoma.