红外激光治疗糖尿病周围神经病变的疗效观察

Improvement of diabetic peripheral neuropathy using monochromatic infrared energy

目的观察红外激光治疗糖尿病周围神经病变的疗效。方法将74例糖尿病周围神经病变患者随机分为常规治疗组(常规组,39例)和红外激光治疗加常规治疗组(红外激光组,35例),通过对足底Semmes-Weinstein单丝(SWME)检测不敏感的位点数、密歇根神经病变评分(MNSI)的综合评定,观察患者是否有感觉功能的恢复及其他神经病变症状的改善,比较2组间疗效。结果经过12次红外激光治疗后,红外激光组患者对足底SWME(5．07级)不敏感的部位明显减少(P＜0．01),密歇根神经病变评分降低(P＜0．01),2组比较差异有统计学意义(P＜0．05)。治疗过程中患者无皮肤损伤。结论红外激光可能是一种安全的、非药物的、非侵入性的糖尿病周围神经病变治疗方法。

Objective To observe the effect of monochromatic infrared energy（MIRE） on diabetic peripheral neuropathy （DPN）. Methods Seventy -four subjects with diabetic peripheral neuropathy who were tested by Semmes-Weinstein monofilaments （ SWM ） were randomized into 2 groups： a conventional management group and a conventional management plus MIRE group. Then the patients＇ sensory function and other DPN symptoms were evaluated by the SWME and the score of Michigan Neuropathy Screening Instrument. Results After treatments, there was a decrease （P 〈 0.01 ） in the number of the sites insensitive to SWME （grade 5.07 ） , and MNSI scores were significantly decreased （ P 〈 0.01 ）. The MIRE management was more effective than conventional management, Conclusion Monochromatic infrared energy is perhaps a safe, non-pharmaceutical and non-invasive method for the treatment of diabetic peripheral neuropathy.