摘要
目的探讨慢性肾炎患者外周血CD146表达的意义。方法用ELISA方法(酶联免疫吸附实验)检测11例慢性肾炎患者与10例正常人外周血CD146的表达。结果慢性肾炎患者外周血CD146表达(425.68±87.84 ng/ml)明显高于正常对照组(268.85%±70.90 ng/ml),P<0.01;CD146表达与尿蛋白定量的相关系数为0.08,P>0.05。结论慢性肾炎患者存在CD146的高表达,但与尿蛋白定量并无相关性。
Objective To explore the significance of CD146 in patients with chronic glomerulonephritis. Methods The plasma levels of CD146 were detected by enzyme linked immunosorbent assay （ELISA） in 11 chronic glomerulonephritis patients and 10 normal controls. Results The plasma levels of CD146 in chronic glomerulonephritis patients （425.68 ± 87.84 ng/ml） were significantly higher than that of control group （268.85 ± 70.90 ng/ml） （ P 〈 0.01） .There was no correlation between CD146 and urine protein（ r = 0.08, P 〉 0.05）. Conclusion The chronic glomerulonephritis patients had highly-expressed CD146 in blood, but it had no correlation with proteinuria.
出处
《中国实验诊断学》
2006年第10期1138-1140,共3页
Chinese Journal of Laboratory Diagnosis
基金
上海市卫生局基金项目(044Y07)
关键词
慢性肾炎
CD146
CD146
chronic glomerulonephritis
