应用ROC曲线图评价几项生化指标在胸水中的价值

To assess the value of biochemical indexes in diagnosis of pheural effusion with ROC diagram

目的评价TP、TPR等几项生化指标在胸水中的价值。方法应用ROC曲线图评价74例患者胸水渗出液和漏出液中的TPR、LDHR、CHOLR等。结果TP、LDH、CHOL及TPR、LDHR、CHOLR渗出液组均显著高于漏出液组(P<0.01)。根据ROC曲线,所有测试中TPR的特异性和灵敏度均高于其他指标,其诊断准确性是最高的(94.8%)。根据疾病分组,除LDH在各组间无显著性差异外,其他指标组间比较均有统计学意义(P<0.05)。结论胸水与血清的蛋白比值(TPR)、胸水乳酸脱氢酶(LDH)、胸水胆固醇(CHOL)含量对区分胸水渗出液和漏出液以及鉴别胸水疾病的性质方面具有临床意义,特别是胸水与血清的蛋白比值(TPR)对区分胸水渗出液和漏出液更有意义。

Objective To assess the value of 9 biochemical indexes in diagnosis of pheural effusion. Methods ROC diagram was used to evaluate the TPR, LDHR and CHOLR in the exudates and transudate. Results There was significant diffemee between the levels of TP, LDH, CHOL and the indexes of TPR, LDHR and CHOLR in the exudates were higher than those in the exudates. The specificity and sensitivity of TPR index was the best. Conclusion TPR has play an important role to constitute the distinction between exudate and transudate.