135例慢性胰腺炎临床病例分析

Analysis of 135 cases with chronic pancreatitis.

探讨慢性胰腺炎的不同病因和临床表现特点。回顾性分析本院135例慢性胰腺炎的住院患者的主要病因包括胆道系统疾病(31．85％)和酒精中毒(35．56％),其他病因包括特发性、自身免疫性疾病、外伤或遗传等。酒精性CP临床症状发生的比例较胆源性高,特别是腹痛、腹泻、糖尿病的发生率明显高于胆源性CP。酒精性与非酒精性CP组、对照组相比,TG、HDL-C、G／HDL-C差别显著。胆道系统疾病和酒精中毒为CP主要病因,近年来酒精性因素呈上升趋势。临床表现上,酒精性较胆源性CP的发生率高。TG／HDL-C比值可能有助于鉴别酒精性和非酒精性胰腺炎。

To study the etiology and clinical feature of chronic pancreatitis. The etiology and clinical feature of 135 cases with chronic pancreatitis collected in our hospital from 1994 to 2004 were retrospectively analyzed. The main causes of chronic pancreatitis were biliary diseases （31.85% ） , alcoholic （35, 56% ） , and other causes such as idiopathic, autoimmune diseases, trauma and heredity etc. The frequency of the different kind of clinical manifestations in alcoholic chronic pancreatitis was higher than that in biliary chronic panreatitis. TG, HDL - C TG/HDL - C in patients with alcoholic chronic pancreatitis were obviously different from those in patients with nonalcoholic chronic pancreatitis and controls group. The main etiology of chronic panreatitis is biliary diseases and alcoholic factor. But the alcoholic factor has the increasing inclination in recent years. The frequency of the different kind of clinical manifestations in alcoholic chronic pancreatitis was higher than that in biliary chronic panreatitis, TG/HDL - C ratio probably helps in differentiation in alcoholic and nonalcoholic chronic pancreatitis.