慢性咳嗽患者支气管激发试验结果分析与检查指导

Analysis on Results of Bronchial Provocation Test for Chronic Cough Patients and Examination Guidance

目的了解慢性咳嗽患者组胺支气管激发试验的结果。方法对225例慢性咳嗽患者用肺功能仪测定基础肺功能及吸入不同剂量组胺后的肺功能,对患者检查前、中、后进行指导。结果225例患者支气管激发试验阳性129例(57·3%),阴性78例(34·7%),可疑阳性18例(8·0%),所有患者均顺利完成检查。结论咳嗽变异型哮喘是慢性咳嗽的常见原因,支气管激发试验是诊断咳嗽变异型哮喘的主要方法,做好试验检查指导是患者顺利完成试验,保证检查结果准确,减少试验不良反应的关键。

Objective To discuss the results of histamine bronchial provocation test for chronic cough patients and examination guidance. Methods Basic lung function and lung function after inhaling different doses of histamine were tested by using pulmonary function test apparatus in 225 patients with chronic cough. All patients were subjected to the examination guidance before, during and after the test. Results In 225 patients with chronic cough, 129 cases （57.3%） were positive, 78 cases （34.7%） were negative, and 18 cases （8.0%） were suspiciously positive for the bronchial provocation test. All the patients undertook the test smoothly. Conclusion Cough variant asthma is the common cause of the chronic cough. The bronchial provocation test is the main method to diagnose cough variant asthma. Therefore, in order to let patients in concert with the check and to guarantee the precision of the test result, the key point is to have precise examination and give correct guidance.