摘要
使用立体定向伽玛刀治疗松果体区肿瘤３３例，肿瘤直径（Ｘ＋Ｙ＋Ｚ／３）１０．０～４５．５ｍｍ；平均２３．５ｍｍ；体积０．４～３５．４ｃｍ３，平均１２．１ｃｍ３；肿瘤边缘剂量１４～２０Ｇｙ，平均１５．２±１．７Ｇｙ；中心剂量２５．０～４２．８Ｇｙ，平均３７．３±６．９Ｇｙ；影像定位仪为１．５ＴＭＲ。随访３～１２个月。初步结果表明：病人的临床症状体证明显好转，９个月后肿瘤生长控制率，即治疗有效率为９６．２％，显效率９２．３％，无严重并发症发生。提示γ－刀可作为松果体区肿瘤的有效治疗方法。
3 patients (29 males and 4 females) underwent stereotartic radiosurgery with a 201 60Co sourcesgamma knife for treatment of pineal region tumors.The patient's age ranged from 1.16 to 48 years(mean18.6 years) and Karnofsky Performance Score (KPS) was 60%-90% (mean 70%).The diameter of tumors(x+y+z/3) ranged from 10.0mm to 45.smm(mean 23.5mm). The dose administered to tumor center andmargin was 37.5±6.9Gy(25-42.86Gy) and 15.2±1.7Gy(14-20Gy)respectively.29 patiens were followedup from 3 to 19 months (mean 8 months). The prelimilinary results showed that the patient's symptomsand signs had a significant improvement.The gth month growth control rate of tumor was 96.2%.Nosevere complications occured.So it subjected empirical treatment of pineal region tumors is no longerwarranted,image-guided gamma knife radiosurgery represents a safe and effective method to accurately treat pineal region tumor,and should be the first option in the therapy of pineal tumors.
