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产前筛查血清标记物与产科并发症的关系 被引量：2

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摘要 血清标记物检测作为一种经济有效的监测产科并发症的方法受到关注。就产前筛查中常用的几种血清标记物:人绒毛膜促性腺激素(hCG)、甲胎蛋白(AFP)、妊娠相关蛋白-A(PAPP-A)、未结合雌三醇(u-E3)等分别进行介绍。并对这些血清标记物的来源、影响因素及其不同水平与产科并发症的关系和临床意义进行深入浅出的分析,展望其临床应用和未来发展的前景。
作者 孙亚莉 吕时铭
机构地区 浙江大学医学院附属妇产科医院
出处 《国外医学（妇产科学分册）》 2006年第5期339-342,共4页 Foreign Medical Sciences(Obstet Gynecol Fascicle)
关键词 产前筛查 血清标记物 产科并发症
分类号 R714.2 [医药卫生—妇产科学]
  • 相关文献

参考文献19

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  • 2Kharfi A,Giguere Y,Grandre PD,et al.Human chorionic gonadotropin (HCG)may be a marker of systemic oxidative stress in normotensive and preeclamptic term pregna -ncies.Clin Biochem,2005,195 (7):236-240
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  • 4Brajenovic-Milic B,Trislaric D,Zuvic-Butorac M,et al.Elevated second-trimester free 3-hCG as an isolated finding and pregnancy outcomes.Fetal Diagn Ther,2004,19 (6):483-487
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同被引文献6

  • 1Reynolds T,Vranken G,Van Nueten J,et al. Down's syndrome screening: population statistic dependency of screening performance[J]. Clin Chem Lab Med, 2008,46 (5):639-647.
  • 2Wald N J, Rodeck C, Hackshaw AK, et al. First and second trimester antennal screening for Down's syndrome:the results of the serum,urine and ultrasound screening study (SURUSS)[J]. J Med Screen, 2003, 10(2):56-104.
  • 3Summers AM, Farrell SA, Huang T, et al. Maternal serum screening in ontario using the triple marker test [J].J Med Screen, 2003,10(3) ; 107-111.
  • 4Benn PaA,Egan JFX,Fang M, et al. Changes in the utilization of prenatal diagnosis[J]. Am Col Obs Gyn, 2004,103 (6) : 1255-1260.
  • 5段红蕾,李洁.唐氏综合征产前筛查策略的研究进展[J].中国优生与遗传杂志,2008,16(6):7-9. 被引量：10
  • 6徐峰,冯泽蛟,李丽洁,严育宏,唐少华,杨雪梅.产前筛查母血清标志物与产科并发症关系的研究[J].中外医疗,2010,29(8):4-6. 被引量：2

引证文献2

二级引证文献8

国外医学（妇产科学分册）
2006年 第5期

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