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伤害性刺激对家兔定量药物脑电图β频段的影响 被引量：9

Effect of nocuous stimulation on β-band of quantitative pharmaco-EEG in rabbits
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摘要 Objective To study the effects of nocuous stimulation onβ-band of QPEEG in rabbits.Methods Rabbits of both sexes were randomly divided into 3 groups: mopping group;forceps holder group;cutting group.According to it,different stimulation were given to the rabbits which had been injected muscle relaxant by vein.The EEG sample was obtained before and at some intervals following the stimulation given to.The EEG activity was processed with the power spectral analysis.Results The percentage of β-band power showed no significant changes in group of mopping(P>0.05);the percentage ofβ-band power were increased(P<0.05) in group of forceps holder within 30 s^60 s after received stimulation in the areas of forehead and cupula,especially in the left areas;the percentage ofβ-band power in group of cutting increased more significantly in all areas of brain(P<0.01).The changes lasted for 2 min.Conclusion After given nocuous stimulation,the percentage of β-band power increased,which showed that the percentage of β-band power would be an effective means of monitoring pain. Objective To study the effects of nocuous stimulation onlY-band of QPEEG in rabbits. Methods Rabbits of both sexes were randomly divided into 3 groups： mopping group; forceps holder group; cutting group. According to it , different stimulation were given to the rabbits which had been injected muscle relaxant by vein . The EEG sample was obtained before and at some intervals following the stimulation given to . The EEG activity was processed with the power spectral analysis. Results The percentage of β-band power showed no significant changes in group of mopping（ P 〉 0.05 ） ; the percentage of β-and power were increased （ P 〈 0.05 ） in group of forceps holder within 30 s - 60 s after received stimulation in the areas of forehead and cupula, especially in the left areas ; the percentage of β-band power in group of cutting increased more significantly in all areas of brain（ P 〈 0.01 ）. The changes lasted for 2 min. Conclusion After given nocuous stimulation, the percentage of β-band power increased, which showed that the percentage of β- band power would be an effective means of monitoring pain.
作者 孔莉 戴体俊 陈 郭忠民 吴克俭 吴海生 曾因明
机构地区 江苏省麻醉医学研究所
出处 《国际麻醉学与复苏杂志》 CAS 2006年第5期287-289,共3页 International Journal of Anesthesiology and Resuscitation
基金 国家自然科学基金资助项目(30471657 39970715) 江苏省科委社会发展研究计划项目(BS2000052) 江苏省自然科学基金资助项目(BK200143)
关键词 定量药物脑电图 伤害性刺激 β频段 听觉诱发电位指数 麻醉深度监测 监测方法 家兔 脑电双频指数 nociceptive stimulation quantitative pharmaco-EEG β-rhythm analgesia
分类号 R614 [医药卫生—麻醉学]
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参考文献5

  • 1Sebel PS, Lang E, Rampil IJ, et al. A multicenter study of bispectral electroencephalogram analysis for monitoring anesthetic effect. Anesth Analg, 1997,84(4) :891-899.
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二级参考文献20

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国际麻醉学与复苏杂志
2006年 第5期

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