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慢性疼痛基因治疗相关研究的进展 被引量：2

Advances in the study on gene therapy for chronic pain
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摘要 Chronic pain is associated with alterations of neuronal systems involved in pain processing.Some suffering patients are not satisfactorily managed with currently available treatments.However,advances in the field of vector systems which have lower levels of inflammatory and immune responses,along with significant increases in our understanding of pain generating mechanisms and knowledge of tight control of transgene expression,will make gene-based approaches for the future management of pain a conceivable reality. Chronic pain is associated with alterations of neuronal systems involved in pain processing. Some suffering patients are not satisfactorily managed with currently available treatments. However, advances in the field of vector systems which have lower levels of inflammatory and immune responses, along with significant increases in our understanding of pain generating mechanisms and knowledge of tight control of transgene expression, will make gene - based approaches for the future management of pain a conceivable reality.
作者 董刚 俞卫锋
机构地区 上海第二军医大学附属东方肝胆外科医院麻醉科
出处 《国际麻醉学与复苏杂志》 CAS 2006年第5期316-319,共4页 International Journal of Anesthesiology and Resuscitation
关键词 慢性疼痛 基因治疗 伤害感受器 中枢敏化 感觉神经纤维 组织损伤 花生四烯酸 预警信号 chronic pain gene therapy vector
分类号 R402 [医药卫生—临床医学]
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参考文献20

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二级参考文献25

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共引文献10

同被引文献24

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国际麻醉学与复苏杂志
2006年 第5期

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