心肌梗塞后倍他乐克与他汀类药物对心脏的保护

The Protective Effect of Betaloke and Statins to Heart after Acute Myocardial Infarction

目的:观察急性心肌梗塞(AMI)患者服用倍他乐克、他汀类药物后对心脏的保护作用,了解其对AMI早期治疗及预后的重要意义。方法:分析因AMI入院者服用倍他乐克、他汀类降脂药物、抗血小板药及硝酸酯类药物的情况和血清胆固醇水平;并与只服用抗血小板药及硝酸酯类药物的AMI患者比较。结果:应用倍他乐克、他汀类药物治疗并追踪4～12个月,患者心功能明显地缓解,血脂水平正常,心电图正常,心脏在原基础上无增大表现。结论:倍他乐克、他汀类药物的早期应用对AMI患者的治疗及预后有益,对防止心肌肥大及心室重塑有效。

Objective： To observe the protective effect of betalode and statins to heart, after the acute myocardial infarction （AMI）, and to understand the value of their application in early treatment and prognosis of the disease. Methods： Sixty-three cases of AMI hospitalized from January, 2003 to August, 2004 were reviewed. The general condition and serum cholesterol level of 33 cases who had been given betalode, statins, antiplatelet drug, and nitric acid ester, were compared with those of 30 cases who had been given antiplatelet drug and nitric acid ester only. Results： After 4 - 12 months of treatment with betaloke and statins, the heart function of patients was markedly improved, blood-lipid levels dropped into normal range, electrocardiogram showed normal, and cardiac enlargement almost stopped. Condusions： The early application of betaloke and statins is valuable for the treatment and prognosis of AMI, and is also effective for prevention of cardiac enlargement, and the rebuilding of ventriculus cordis.