糖尿病性黄斑水肿的视网膜厚度和视野检查分析

Retinal thickness and the visual field in diabetic macular edema

目的探讨糖尿病性黄斑水肿(diabetic macularedema,DME)的结构与功能检查及主观检查与客观检查之间的关系。方法对正常对照组20例(30眼)、DME 69例(131眼)行光学相干断层扫描(optical coherence tomography,OCT)、荧光素眼底血管造影(fundus fluorescein angiography,FFA)、视野检查,其结果进行对比分析。结果黄斑中心厚度和黄斑光敏感度、黄斑中心厚度与视力、黄斑光敏感度与视力都显著相关,黄斑厚度图与FFA对黄斑异常的检出率无区别。结论随着黄斑结构的改变,DME患眼的视功能也相应地发生一定的变化,但两者并不完全一致,OCT和视野计的联合运用才能全面、客观地反映黄斑情况。结构和功能检查方法各有自己的优势,它们的联合运用有利于DME的早期诊断。

Objective To investigate the relationship between structure and function in diabetic macular edema （DME）.Methods Optical coherence tomography （OCT）, fundus fluorescein angiography （FFA） and visual field measurements were used for comparative analyses in 30 normal eyes of 20 volunteers and （69 cases） 131 eyes with diabetic macular edema （DME）. Results The correlations between macular central thickness and macular visual sensitivity, macular central thickness and visual acuity, and macular sensitivity and visual acuity （ r = 0. 663 ; P 〈 0.01） were statistically significant. The differences between the macular thickness map findings and the FFA in macular abnormality were not statistically significant. Conclusion When macular structure was altered, there were corresponding changes in the visual function of DME eyes to some extent. However, visual functons were not in complete accord with macular structure. The condition of the maocular area could be fully and objectively displayed only with OCT and perimetry. OCT and perimetry are each superior in their own way. Taken together, they can assist in the early diagnosis of DME.