降钙素原对细菌感染性发热快速辅助诊断的价值

Value of Procalcitonin(PCT) in the Auxiliary Diagnosis of Bacteria Infective Fever

目的探讨血清降钙素原(procaic iton in,PCT)检测在临床上快速辅助诊断细菌感染性发热病人的作用。方法设2个研究组和1个对照组。研究组分别为经临床医师确诊的严重细菌感染性病人组和轻度细菌感染性病人组,对照组的病人未发生任何感染。分别测定各研究组和对照组的血清PCT、C-反应蛋白(CRP)、血沉(ESR)水平并对病人进行白细胞计数。结果细菌感染性发热病人PCT水平升高,并随感染程度的加重PCT升高更加明显(P<0.01),各研究组与对照组相比,差异均具有统计学意义(P<0.01)。结论血清PCT水平测定可作为细菌感染性发热的较敏感的快速辅助诊断方法。

[ Objective] To explore the effect of procalcitonin （PCT） detection on the clinical rapid diagnosis of bacteria infective fever. [ Methods] 2 ease groups and 1 control group were founded. Cases in ease group Ⅰ were the diagnosed severe bacteria infective fever patients, those in ease group Ⅱ were the diagnosed slight bacteria infective fever patients, those in the control group were non - infected patients. Serum concentration of PCT, CRP and ESR in the ease groups and the control group were determined; the leucocyte number of the patients was counted. [ Results] The serum concentration of PCT increased among the bacteria infective fever patients, and increased more significantly with the deterioration of infection （ P 〈 0. 01 ） ; the difference was significant compared with the control group （ P 〈 0. 01 ）. [ Conclusion] Serum PCT concentration determination can be used as a rapid auxiliary diagnostic method for bacteria infective fever.