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拮抗转化生长因子β活性对糖尿病肾病的防治作用 被引量:1

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作者 肖新怀 陈澍
出处 《中国药物与临床》 CAS 2006年第10期725-727,共3页 Chinese Remedies & Clinics
基金 广州市卫生局中医科研基金资助项目(2005A50)
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  • 1Chen S,Jim B,Ziyadeh FN,et al.Diabetic nephropathy and transforming growth factor-beta:transforming our view of glomerulosclerosis and fibrosis build-up.Sermin Nephro,2003,23 (6):532-543.
  • 2Wolg G,Chen S,Ziyadeh FN,et al.From the periphery of the glomerular capillary wall toward the center of disease:podocyte injury comes of age in diabetic nephropathy.Diabetes,2005,54(6):1626-1634.
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  • 4Patel A,Scott WR,Lympany PA,et al.The TGF-beta 1 gene codon 10 polymorphism contributes to the genetic predisposition to nephropathy in Type 1 diabetes.Diabet Med,2005,22 (1):69-73.
  • 5Zheng F,Fomoni A,Elliot SJ,et al.Upregulation of type I collagen by TGF-beta in mesangial cells is blocked by PPARgamma activation.Am J Physiol,2002,282(4):639-648.
  • 6Yamagishi S,Inagaki S,Okamoto T,et al.Advanced glycation end products inhibit de novo protein synthesis and induce TGF-beta overexpression in proximal tubular cells.Kidney Int,2003,63(2):464-473.
  • 7Weigert C,Brodbeck K,Klopfer K,et al.Angiotensin Ⅱ induces human TGF-beta 1 promoter activation:similarity to hyperglycaemia.Diabetologia,2002,:5(6):890-898.
  • 8Isono M,Mogyorosi A,Han DC,et al.Stimulation of TGF-beta type Ⅱ receptor by high glucose in mouse mesangial cells and in diabetic kidney.Am J Physiol Renal Physiol,2000,278 (5):830-838.
  • 9Chen S,Iglesias MC,Jim B,et al.Reversibility of established diabetic glomerulopathy by anti-TGF-beta antibodies in db/db mice.Biochem Biophys Res Commun,2003,300(1):16-22.
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