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西妥昔单抗单药或与伊立替康联合治疗伊立替康耐药的转移性结直肠癌 被引量:14

Cetuximab Monotherapy and Cetuximab plus Irinotecan in Irinotecan-Refractory Metastatic Colorectal Cancer
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作者 徐建明 张华
出处 《循证医学》 CSCD 2006年第5期274-276,共3页 The Journal of Evidence-Based Medicine
关键词 转移性结直肠癌 西妥昔单抗 伊立替康 metastatic colorectal cancer Cetuximab Irinotecan
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参考文献6

  • 1De Gramont A, Figer A, Seymour M, et al. Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer [J]. J Clin Oncol, 2000, 18:2938-2947.
  • 2Douillard JY, Cunningham D, Roth AD, et al. Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomized trial [J]. Lancet, 2000,355:1041-1047.
  • 3Herbst RS, Shin DM. Monoclonal antibodies to target epidermal growth factor receptor positive tumors:a new paradigm for cancer therapy [J]. Cancer, 2002,94: 1593-1611.
  • 4Hurwitz H, Fehrenbacher L, Novotny W, et al. Bevacizumab plus irinitecan, fluorouracil, and leucovorin for metastatic colorectal cancer [J]. N Engl J Med, 2004,350:2335-2342.
  • 5Lievre A, bachet JB, Le Corre D, et al. KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer [J]. Cancer Res, 2006,66: 3992-3995.
  • 6Moroni M, Veronese S, Benvenuti S, et al. Gene copy number for epidermal growth factor receptor (EGFR) and clinical response to antiEGFR treatment in colorectal cancer:a cohort study [J]. Lancet Oncol, 2005,6: 279-286.

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