葛根膳食纤维对小白鼠降血糖的影响

Effect of dietary fiber from pueraria radix on the hyperglycemia mice

以葛根膳食纤维(DF)为原材料,以正常小白鼠空腹血糖值、四氧嘧啶所致高血糖小白鼠的血糖值和糖耐量为评价指标,分别讨论酶法制备的葛根膳食纤维(DF1)和化学法制备的葛根膳食纤维(DF2)对小白鼠血糖调节功能的影响。结果表明:灌胃DF72h血糖值比起模型对照组均有下降,但不显著(P>0.05);灌胃6d后,中高浓度DF1以及葛根渣组的小白鼠血糖值显著下降(P<0.05);灌胃17d之后,发现除了DF2,其它组动物的血糖值均有极显著的降低(P<0.01)。由此可以说明,葛根DF可预防糖尿病,治疗由四氧嘧啶所致的糖尿病,改善由四氧嘧啶所致糖尿病小白鼠的糖耐量。

Influences of dietary fiber （DF）, which were processed by enzyme-method （ DF1 ） and chemical-method （ DF2 ） , on the hyperglycemia mice clue to alloxan were evaluated by the indices of the blood sugar concentration and the glucose tolerance, After perfusing DF for 72 hours, the blood sugar concentration of the mice declined but not salient （p 〉 0,05）, as compared with model control group; for 6 days, the middle and high concentrations of DF1 , and Pueraria dregs could obviously decline the blood sugar concentration of the mice （ p 〈 0.05） ; for 17 days, the blood sugar of all groups except DF2 declined remarkably （ p 〈 0.01 ）. This suggested that diabetes caused by alloxan could be prevented and cured, and the glucose tolerance of the hyperglycemia mice due to alloxan could be improved by intaking Pueraria DF.