28例肝内胆管细胞癌手术治疗分析

Analysis of operative treatment of patients with cholangiocarcinoma

目的提高肝内胆管细胞癌的诊断和治疗水平,分析其临床特点及预后相关因素。方法回顾性分析中国医学科学院肿瘤医院1970至2005年外科治疗的28例肝内胆管细胞癌患者的临床资料。结果28例患者中AFP阳性率为10.7%(3/28),肝硬化阳性率25.0%(7/28)。根治性切除组1,3,5年生存率分别为82.3%、45.8%和45.8%;姑息性切除组1,3年生存率分别为11.1%和0。结论肝内胆管细胞癌以手术治疗为主。根治性手术切除是获得长期生存的惟一途径。

Objective To improve the diagnosis and treatment of the cholangiocarcinoma and analyze the clinical characteristics and the prognosis. Method Twenty-eight cases of the cholangiocarcinoma from 1970 to 2005 were analyzed retrospectively. Results In 28 cases, the positive rates of AFP and liver cirrhosis were 10.7% and 25.0% respectively. The 1-,3-,5-year survival rate were 82.3% ,45.8% and 45.8% in the patients with radical operation and 11.1% ,0 in those with non-radical operation. Conclusion Operation is the effective treatment for the cholangiocarcinoma. Radical operation is the only way for obtaining long-term survival.