阻塞性睡眠呼吸暂停综合征患者心律失常的临床分析

Clinical analysis of cardiac arrhythmia in patients with obstructive sleep syndrome

目的探讨阻塞性睡眠呼吸暂停综合征(obstructive sleep apnea syndrome,OSAS)与心律失常的关系。方法对经多导睡眠仪监测(polysomnography,PSG)确诊的OSAS 69例患者行24h动态心电图(Holter)监测,同时选择21例单纯鼾症患者作为对照组。结果OSAS组患者体重、呼吸暂停低通气指数(apnea hypopnea index,AHI)和最低血氧饱和度(1owest satura-tion,LSaO2)与对照组差异有统计学意义(P<0.05、P<0.01);OSAS组心律失常发生率为62.32%,并且随OSAS病情加重,心律失常发生率升高、时间延长及恶性程度加重。结论OSAS患者心律失常的发生与呼吸暂停低通气指数及低氧血症密切相关。

Objective To explore the relationship between obstructive sleep apnea syndrome（OSAS） and arrhythmia. Methods Sixty-nine patients with OSAS and 21 simple snores confirmed by polysomnography（PSG） were analyzed by 24h Holter. Results The weight,apnea hypopnea index（AHI）and lowest saturation（LSaO2 ） in OSAS group were significantly higher than those of the control group. The incidence of cardiac arrhythmia in OSAS group was 62.32% and was increased with the severity of OSAS. Conclusion The occurrence and degree of cardiac arrhythmia in patients with OSAS is closely related with AHI and nocturnal hypoxemia.