G~－菌感染对重型病毒性肝炎并多器官功能衰竭的影响

Effect of G^- Bacillus Infection on Severe Virus Hepatitis with Multiple System Organ Failure

本文对１９９０－１９９５年间４２例死亡的重型肝炎临床资料进行了分析．发现其中有３６例发生了多器官功能衰竭，这与细菌感染有密切关系，机率为８５．７％，Ｇ－菌培养阳性率为７４．１％，主要为内源性大肠杆菌，克雷白氏杆菌、变形杆菌及肠杆菌属细菌。原发性腹膜炎１８例（５０％），胆系感染９例（２２．２％），支气管肺炎６例（１６．６％），尿路感染３例（８．３％）．临床表现常为隐匿性，早期临床症状及体征多不明显易漏诊．本文结合文献对Ｇ－菌并发多器官功能衰竭作用及防治进行了探讨．

We analysed the of imcal data of 42 dead pat lents who suffered from severe virtus hepatitis in our hospital from 1990 to 1995. Among them 36 patients had multiplee system organ failure, the positive rate was 85. 7%, the positive rate of bacterial culture was 74. 1%, the main bacteroides was endogenous E. coli, Klebsiella pneumoniae, Bacillus proteus and other nitest me bacteroides. 18 pat lents had primary peritomtis (50%), 9 had biliary system infect ion (22. 2%), 6 had bronchopneumonia (16. 6 % ), 3 had urinary tract infection (8. 3 % ). Clinical symploms of all these patients usually were not obvious, their early symptom and sign were not clear, so missed diagnosis usually was occuled.