颅内肿瘤X-刀治疗近期疗效观察

Observations on the Short Term Effects of X-Knife Treatment for Intracranial Neoplasms

目的:探讨X-刀对颅内肿瘤的治疗作用。方法:观察X-刀治疗93例颅内肿瘤患者的近期治疗效果。71例得到随访,平均随访4.65月。结果:肿瘤局部控制率％.3％,病情稳定好转率80.30％。大病变和小病变的肿瘤控制率相近,但大病变术后脑水肿的机会较多而严重、患者的生存质量也差。结论:X-刀对颅内肿瘤有肯定治疗作用,严格选择病变大小、正确选择限光筒、照射弧和剂量,合理使用低剂量分次治疗是提高疗效的有效措施。

Objective: To study the treatment effects of X - Knife for intracranialneoplasms. Method: Observed the short term effects of X - Knife treatment in 93 patients withintracranial neoplasms. 71 cases were followed up, and the median follow - up time was 4.65months. Results: The efficiency of local neoplasm control was 96.3%, and that of stability andimprovement were 80.30%. The efficiency of neoplasm control was no difference in twe series of largeand small lesions. But the large lesions had a higher possibility of post - treatment cerebral edema, whichwas often more severe, and those patients had bad living quality also. Conclusion: X - Knife treatmentshows definite therapeutic effects for the intracramial neoplasms. Selecting the size of the lesions fortreatment, choosing the collimators, irrdiation arcs and the treatment dose accurately, and applying thefractional low single - dose treatment properly, were the useful management to improve the effects.