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丁酸钠诱导人肝癌细胞凋亡机制 被引量:4

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摘要 丁酸钠(NaB)作为一种组蛋白去乙酰化酶(HDAC)抑制剂,已被证实能抑制多种体外培养的肿瘤细胞增殖、诱导肿瘤细胞衰老和凋亡。我们拟用NaB作用于人肝癌SMMC-7721细胞,采用FCM检测细胞周期、逆转录-聚合酶链反应(RT—PCR)方法及Western blot方法在mRNA及蛋白水平检测p21WAF。
出处 《中华实验外科杂志》 CAS CSCD 北大核心 2006年第11期1412-1412,共1页 Chinese Journal of Experimental Surgery
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同被引文献26

  • 1杨维良,张东伟.乳腺癌基因治疗的研究现状及展望[J].中华实验外科杂志,2005,22(5):633-635. 被引量:15
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