金属—有机刚性模块的形成与结合鞣协同效应

The Being of Metal-organic Rigid Matrix and Synergistic Effect of Combination Tannage

通过两种非Cr材料结合鞣产生协同效应(Synergistic Effect)是提高皮胶原蛋白耐热稳定性的重要途径。已研究及实践的结果间接证明了产生协同效应的原因是两种鞣制用的材料在皮胶原纤维间聚合形成了一种刚性模块(Rigid Matrix)。这种Rigid Matrix结构稳定且耐热性好,由此阻止了胶原分子在受热时造成的构型及构像的转变。为了进一步明确刚性模块的鞣制机理,应该研究金属-有机、有机-有机的两类RigidMatrix在皮胶原的内外形成过程、结构特征与耐热稳定性进行对比分析研究,探索这些Rigid Matrix的结构性能与结合鞣协同效应的内在关系。研究成果将对丰富鞣剂鞣法理论、推动无Cr鞣革工业化进程有重要意义,对硬蛋白组织工程材料的耐热性研究有借鉴意义。

The Synergistic Effect will occur with two non-chrome materials combination tannage and can improve the hydrothermal stability remarkably. The research has proved that it is because that there forms the Rigid Matrix between two tanning agents. Because of stable structure, good resistant stability, the Rigid Matrix can prevent the conformation change of collagen molecule when heated. In order detail information, the being process, structure and resistant stability of the Rigid Matrixes including metal-organic materials, organic-organic materials should be studied respectively. If the Rigid Matrix can be explained completely, it will contribute to establish non-chrome tanning process and probe the resistant heat materials of protein matters.