摘要
吡喹酮是一种广谱抗蠕虫药,它的抗虫作用具有免疫依赖性和免疫协同性。该文概述了其免疫依赖性和免疫协同性的发现过程及有关证据,推断了其作用机制,介绍了吡喹酮与一些免疫因子抗日本血吸虫的协同作用以及吡喹酮抗虫治疗对宿主免疫功能的影响,并提出了需要继续探讨的问题。
Praziquantel is an anthelmintic with a wide spectrum of activity against parasitic trematodes and cestodes. Its efficacy is of immune-dependence and immune-synergy. This article presents the discovery and evidence of the immune-dependence and immune-synergy, and extrapolates the mechanism of action. This article also introduces the synergic effect of praziquantel with rome immune factors and the impact on the host＇s immune system with pranziquantel treatment, and discusses some aspects for future researches.
出处
《国际医学寄生虫病杂志》
CAS
2006年第5期256-260,共5页
International JOurnal of Medical Parasitic Diseases
关键词
吡喹酮
免疫依赖性
免疫协同性
Praziquantel
Immune-dependence
Immune-synergy
