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FcγRⅢ研究进展 被引量：2

Recent Advance in FcγRⅢ
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摘要 作为免疫球蛋白与免疫细胞的桥梁,FcγRⅢ(FcγreceptorⅢ)在机体免疫与免疫细胞功能发挥中具有重要作用。近来研究表明,FcγRⅢ与自身免疫疾病的发生和预后有明确的关系,而其介导DC细胞成熟、在NK细胞和巨噬细胞的ADCC作用中所具有的重要作用使人们认识到FcγRⅢ有望成为肿瘤和免疫疾病治疗的重要靶向。 As the bridge between immunoglobin and immune cells, FcγRⅢ （Fcγ receptor Ⅲ ） plays important roles in immune response and function of immune cells. Recent studies indicate that FcγR Ⅲ has obvious correlation with the falling and prognosis of autoimmune diseases. The importance of FcγR Ⅲ in the mature of DCs, the ADCC of NK cells and macrophages made it possible to be the important therapeutic targets to tumor and autoimmune disease.
作者 丁雄 龚建平（审校）
机构地区 重庆医科大学附属第二医院肝胆外科 重庆医科大学附属第二医院肝胆外科
出处 《国际免疫学杂志》 CAS 2006年第6期373-376,共4页 International Journal of Immunology
关键词 免疫球蛋白 受体 免疫细胞 Immunoglobin Receptor Immune cells
分类号 R392.11 [医药卫生—免疫学]
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参考文献18

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同被引文献26

  • 1吴昌平,蒋敬庭,邓海峰,陆明洋,李敏,王赫,吴骏,张红宇,季枚,赵伟庆.CIK细胞体外培养的免疫表型[J].江苏医药,2005,31(9):644-645. 被引量：20
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  • 6Odman-Ghazi SO, Hatcher F, Whaien MM. Expression of functionally relevant cell surface markers in dibutyltin-exposed human natural killer cells. Chem Biol Interact. 2003;146(1):1-18.
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  • 8Moga E,Alvarez E,Canto E,et al.NK cell stimulated with IL-15 or CpG OND enhance rituximab-dependent cellular cytotoxicity against B-ceU lymphoma.Exp Hematol.2008;36(1):69-77.
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国际免疫学杂志
2006年 第6期

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