甲硝唑等保留灌肠治疗溃疡性结肠炎48例疗效观察

Therapeutic Effect of Retention Enema with Mixture of Metronidazole, Dexamethasone,Anisodamine Hydrochloride and Gentamicin in the Treatment of Ulcerous Colitis：Analysis of 48 Cases

为探讨溃疡性结肠炎更好的治疗方法，对确诊为溃疡性结肠炎的患者48例采用0．2％甲硝唑80ml、地塞米松10mg、盐酸山莨菪碱10mg、庆大霉素16万U混合液保留灌肠治疗。48例中治愈27例，显效14例，好转5例，有效率95.8％，经随访6例复发，复发率13.0％。该方法操作简单，药物价格低廉，易得，患者痛苦小，依从性好，副作用小，疗效显著，是治疗溃疡性结肠炎的理想方法。

Retention enema with mixture of 4 drugs was tried for the objective of probing into a better therapeutic effect in the treatment of ulcerative colitis. The therapeutic scheme included metronidazole （0.2 %, 80ml） ,dexamethasone （10mg）,anisodamiue hydrochloride （10mg） and gentamicin（160000U）,which were made into a mixture fluid for enema. After enema treatment, cure was achieved in 27 cases, notable effectiveness in 14 and improvement in 5 in all the 48 cases,and the effective rate was 95.8%. Recurrence was found in 6 cases（13. 0%） during follow-up. It is suggested that this medical therapy is an ideal one for its advances in simple manipulation, cheap cost, less pain, less side effect and better therapeutic result.