期刊文献+

血管内皮在心血管生理和病理中的作用

THE ROLE OF VASCULAR ENDOTHELIUM IN CARDIOVASCULAR PHYSIOLOGY AND PATHOLOGY
下载PDF
导出
摘要 血管内皮是一个重要的调节器官。正常血管内皮介于循环血液和组织之间,对其物理、化学及激素环境变化能产生相应的生物活性物质,用以调节血管平滑肌张力,保持血管壁光滑,介导血液自稳、细胞增殖及血管壁的炎症、免疫反应和血液的流动性。损伤或激活内皮,会削弱正常的内皮调节功能,引起相应的形态和功能的改变,即内皮功能紊乱,导致一系列临床症状。尽管还没有直接治疗内皮功能紊乱的药物,但现有的基于内皮功能紊乱的病机知识而采取的治疗手段仍取得了较好疗效。新的关于内皮功能紊乱发生的分子生物学基础的知识,革新的诊断手段,有助于治疗内皮功能紊乱。 Vascular endothelium is an important regulatory organ.Located between circulatory blood and tissue,normal endothelium can produce vasoactive substances which regulate blood vasotone,keep vascular wall smooth and mediate hemostasis,cell proliferation,inflammation,immunization and blood fluidity.Injury or activation of endothelium weakens its regulatory function and results in reciprocal alteration of form and function(that is called endothelium dysfunction)and a series of clinical symptoms.Although there isn′t any drug to directly cure endothelium dysfunction,present management based on pathological knowledge has been proved to be satisfactory.Further biomolecular knowledge on endothelium dysfunction and new diagnostic methods will be helpful to cure endothlium dysfunction.
作者 李三潭
出处 《武汉冶金科技大学学报》 1996年第4期513-519,共7页
关键词 血管内皮 心血管疾病 内皮功能紊乱 vascular endothelium cardiovascular disease endothelium dysfunction
  • 引文网络
  • 相关文献
;
使用帮助 返回顶部