门脉循环γ照相、B超和肝功能测定对肝硬化诊断的对比研究

The Comparative Study of Portal Circulation Imaging.B-mode Ultrasound and Liver Function Tests in the Diagnosis of Liver Cirrhosis

本文应用门脉循环γ照相测定门脉分流指数，评估其在肝硬化诊断中的作用，并与Ｂ超和５组肝功能测定进行对比。研究表明，核素门脉分流指数随着慢性肝病的肝纤维化进程不断升高，正常人＜慢性肝炎＜代偿期肝硬化＜失代偿期肝硬化。本法敏感性为９２．３％，Ｂ超为７７．４％，肝功能总体为７０．９％；本法特异性为１００％，准确率９５．１％，阳性预测值１００％，阴性预测值８８．４％。说明门脉循环γ照相是安全、简便，早期诊断肝硬化的可靠方法。

Portal shunt index was determined by portal circulation scintigraply. and evaluated upon its efficacy on the diagnosis of cirrhosis, and compared with that of B-mode ultrasound and 5 series of liver function tests,The portal shunt index increased with the progress of fibrosis in chronic liver disease. That is,normal control < Chronic hepatitis < compensated cirrhosis < decompensated cirrhosis The sensitivity of portal shunt index, B-mode ultrasound and liver function tests were 92.3%, 77.4% and 70. 9%, respectively. The specificity.accuracy predictive values of positive study and negative study of the nuclide method were 100%, 95.1%, 100% and 88.4%, respectively.Our study demonstrated that the portal circulation scintigraphy was a safe, convenient, new method for the early diagnosis of liver cirrhosis.