胆囊切除术对胃肠功能的影响

Clinical Study on the Influence of Gastrointestinal Function after Cholecystectomy

目的探讨胆囊切除术对胃肠功能的影响。方法对47例单纯胆囊切除患者术后随访3年并对胃行胃液、B超、胃镜等多项指标检测。结果胆囊切除术并不影响空腹12 h胃液的pH值;但使胃排空时间平均延长1.46倍;空腹12 h胆汁反流率、幽门螺旋杆菌感染率明显升高(P<0.01);胃黏膜病变率平均达48.4%。结论胆囊切除术影响胃肠功能,引起胃排空时间延长、胆汁反流、幽门螺旋杆菌感染,最终导致胃黏膜病变。

Objective To study the influence effect of gastrointestinal function after cholecystectomy. Methods 47 patients after cholecystectomy were followed up for three years and five indices were studied. Results No significant pH value variation of gastric juice after cholecystectomy was detected. But delayed gastric empty and elevated incidence of bilereflux P 〈 0.01 ） and Hp infection （P 〈 0.01） were found. Occurrence rate of gastric mucosal lesion was 48.5 %. Conclusion Cholecystectomy may delay gastric empty,cause bilereflux and increase Hp infection rate, and finally gastric mucosal lesion is prone to occur.