期刊文献+

大黄治疗全身炎症反应综合征的探讨 被引量:2

下载PDF
导出
摘要 目的探讨大黄对全身炎症反应综合征(SIRS)的治疗作用。方法对照组(n=25例)予常规病因治疗,治疗组(n=25例)加用生大黄粉10 g口服,不能口服者保留灌肠,连用5天。测定SIRS患者血清CRP、肿瘤坏死因子(TNF-α)、白细胞介素(IL-1β)。结果治疗组治疗前后的CRP、TNF-αI、L-1β值比较差异有统计学意义(P<0.01)。对照组治疗前后比较也有下降,但无统计学意义(P>0.05)。治疗组与对照组治疗前APACHEⅡ评分的比较无显著性差异(P>0.05),治疗后比较有显著性差异(P<0.01)。治疗组MODS发生率明显较对照组低,但比较无统计学意义。结论大黄能明显改善SIRS患者的预后,降低病死率,临床应用有很好的前景。
出处 《右江医学》 2006年第6期597-598,共2页 Chinese Youjiang Medical Journal
  • 相关文献

参考文献5

二级参考文献20

  • 1Duclos T W. Function of c-reactive protein [J]. Ann Med, 2000,32:274-278.
  • 2Volanakis J E. Human c-reactive protein: expression,structure, and function [J]. Mol Immunol,2001,38:189-197.
  • 3Ford E S. Body mass index, diabetes, and c-reactive protein among U S adults [J]. Diabetes Care,1999,22:1971-1977.
  • 4Barzilay J I, Abraham L, Heckbert S R, et al. The relation of markers of inflammation to the development of glucose disorders in the elderly: the cardiovascular health study[J]. Diabetes,2001,50:2384-2389.
  • 5Pickup J C, Crook M A. Is type 2 diabetes mellitus a disease of the innate immune system? [J].Diabetologia, 1998,41:1241-1248.
  • 6Pickup J C, Mattock M B, Chusney G D, et al.NIDDM as a disease of the innate immune system:association of acute phase reactants and interleukin-6 with metabolic syndrome X [ J]. Diabetologia, 1997,40:1286-1292.
  • 7Pradhan A D, Manson J E, Rifai N, et al. C-reactive protein,interleukin 6,and risk of developing type2 diabetes mellitus [J]. JAMA,2001,286:327-333.
  • 8Festa A, Agostno R D, Howard G, et al. Chronic subclinical inflammation as part of the insulin resistance syndrome [J]. Circulation, 2000,102:42-47.
  • 9Oaes O N, Akca H, Nayo L D, et al. A phosphatidylinositol 3 - Kinase / Akt / mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-l[J]. Proc Natl Acad Sci USA,2001,10:4640-4645.
  • 10John A, Colwell M D. Inflammation and diabetic vascular complications [J]. Diabetes Care, 1999,22:1927-1928.

共引文献206

同被引文献23

引证文献2

二级引证文献4

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部