ClearView CT快速诊断女性生殖道沙眼衣原体感染的评价

Evaluation of Clearview CT Rapid Test Kit in Testing for Female Genital Tract Chlamydia Trachomatis Infection

目的:对C learV iew CT快速诊断试剂盒检测女性生殖道的沙眼衣原体进行方法学评价。方法:采集每名受试者宫颈分泌物拭子2份,将之随机分为2组,以荧光定量PCR为参比试验,评价C lear-V iew CT快速诊断试剂盒在女性生殖道沙眼衣原体感染的应用性能。结果:设置荧光定量PCR为参比试验,C learV iew快速诊断试剂盒检测女性生殖道衣原体的敏感性为32.73%,特异性为88.52%,约登指数为0.2125。在感染率为28.95%的性服务工作者人群中应用该试剂盒检测生殖道沙眼衣原体时,其验后概率为53.74%。结论:C learV iew CT快速试剂盒的特异性尚可,但其敏感性差;在感染率达28.95%的女性性服务工作者人群应用C learV iew快速试剂盒检测生殖道衣原体感染,检测阳性者来诊断衣原体感染的把握度为53.74%。

Objective： Evaluate clearview CT rapid test kit in testing for female genital tract chlamydia trachomatis infection. Methods ：Two vaginal swabs from each participant were collected and samples were divided into two groups randomly, fluorescent quantitation PCR has been taken as a reference, clearview CT rapid test kit to be used in chlamydia trachomatis detected. Results： The clearview rapid test kit had a sensitivity of 32.73%, a specificity of 88.52% and a Youden index of 0. 2125. Female commercial sex worker （FCSW） population with an infection rate of 28.95%, and the posterior probability was 53.74%. Conclusion ：The clearview CT rapid test kit showed adequate specificity and low sensitivity. FCSW with an infection rate of 28.95%, whom detected by clearview rapid test kit, was found a CT infection rate of 53.74%.