荧光定量PCR检测HSV合并其他性传播感染结果与分析

The results and analysis of FQ-PCR detecting HSV infectors with other veneral disease

目的探讨生殖器疱疹患者单纯疱疹病毒(HSV)及其他性传播感染的发病率及特点。方法采集182例生殖器疱疹患者的损害部位的组织液或阴道分泌物,用荧光定量PCR(FQ-PCR)方法,检测单纯疱疹病毒、人乳头状瘤病毒、沙眼衣原体、解脲支原体等性传播病原体,梅毒、抗H IV采用血清学试验。结果182例生殖器疱疹患者中,HSV阳性116例(63.7%),在116例阳性HSV中有32例(27.6%)合并有其他性传播感染,其中合并人乳头状瘤病毒感染11例(9.5%),梅毒8例(6.9%),沙眼衣原体4例(3.4%),解脲支原体9例(7.8%)。结论HSV感染是生殖器疱疹的主要原因,并且容易合并其他性传播感染,应注意检查及治疗。

Objective To investigate the infection rate and its and other venereal disease in Herpes genitalis patients. Methods charactor ot herpes simplex virus （HSV） Secretions from lesion site or vagina of 182 herpes genitalis patients were collected. HSV, Human papillomavirus （HPV） , chlamydia and mycoplasm were detected by fluorogenic quantitative PCR （FQ -PCR）. Syphilis and anti -HIV were dected by serology tests. Results In the all 182 herpes genitalis patients,ll6 patients were HSV positive（63.7% ） ,and 32 patients （27.6%） were with other veneral diseases at the same time. The number of HPV,syphilis, chlamydia and mycoplasm infectors were 11 （9.5 % ）, 8 （ 6.9% ）, 4 （ 3.4% ） and 9 （ 7.7 % ） respectively. Conclusion HSV infection is the main cause of herpes genitalis, and is easy to be with other veneral diseases at the same time. Dection and therapy should be paid attention.