硬膜外腔注入麻黄碱预防阻滞后低血压

Effect of Injection Ephedrine into Epidural Space in Prevention of Epidural Anesthesia Hypotension

目的硬膜外腔注入麻黄碱预防硬外阻滞后低血压。方法选择204例心功能正常,在硬膜外麻醉下施腹部手术的患者,随机分为对照组(n=104)和观察组(n=100)。对照组局麻药为2%利多卡因20m l;观察组局麻药为2%利多卡因20m l加入麻黄碱15mg(0.075%)。结果观察组硬膜外阻滞后SBP、DBP、MAP、HR与阻滞前比较均差异无统计学意义(P>0.05);而对照组硬膜外阻滞前后SBP、DBP、MAP、HR比较差异有统计学意义(P<0.05);硬膜外阻滞后SBP、DBP、MAP、HR在两组间差异有统计学意义(P<0.05)。结论硬膜外腔注入0.075%麻黄碱对硬膜外阻滞后低血压具有预防作用,特别对体质差、阻滞平面较广和施剖宫产术的患者有良好效果。

Objective To investgate the effect of injection of 0. 075% Ephedrine into epidural space in prevention of epidural anesthesia hypotension. Methods 204 ases, all of abdominal operation under epidural anesthesia with normal heart function, were investgated ,which were divided into research group（ n = 100）and control group（ n = 104）. Local anesthetic of control group was 2% Lidocaine 20ml;local anesthetic of research group was 2% Lidocaine and Ephedrine 15mg（0. 075% ）. Results There was no significant differences between pre - anesthsia and post - anesthesia of SBP, DBP,MAP ,HR in control group and those of after epidural anesthesia between two group（ P 〈 0. 05 ）. Conclusion There are contribution of injection of 0. 075% Ephedrine into epidural space to prevent epidural anesthesia hypotension. Especially in those who were weak body or extensive anesthesia - level or cesarean section.