心先安佐治婴幼儿急性毛细支气管炎观察及护理

Clinical observation and nursing of Meglumine adenosine cyclophosphate injection as add-on treatment for acute bronchiolitis in infants

目的：探讨心先安在治疗婴幼儿急性毛细支气管炎中的临床疗效及护理方法。方法：112例急性毛细支气管炎患儿随机分为治疗组及对照组，在相同的基础治疗条件下，治疗组应用心先安每次2～5mg／kg，静滴，每天2次。结果：治疗组：痊愈41例（73．2％），好转10例（17．9％），无效5例（8．9％），总有效91．1％。对照组痊愈34例（60．7％），好转8例（14．3％），无效14例（25％），总有效75％。两组相比差异显著（x^2=5．13，P〈0．05）。结论：心先安佐治婴幼儿急性毛细支气管炎疗效确切，且安全、可靠。细致的观察和护理是治疗成功的关键之一。

Objective：To explore the clinical efficacy of Meglumine adenosine cyclophosphate injection for acute bronchiolitis in infants. Methods：112 patients with acute bronchiolitis were randomly divided into treatment group（ Meglumine adenosine cyclophosphate injection group）and control group. On basis of same therapy conditions in both groups, treatment group received Meglumine adenosine cyclophosphate injection 2 - 5 mg·kg^-1, ivgtt, bid. at the same time, we observed the improvement of acute bronchiolitis and adverse reactions by nursing measures carefully. Results： The clinical total effective rate, remarkable effective rate, effective rate and ineffective rate were 91.1% ,73.2% ,17.9% ,and 8.9% in treatment group and those in control group were 75% ,60.7% ,14.3% and 25% , respectively. There was significant difference between two groups （x^2 = 5.13, P 〈 0.05 ）. Conclusions： Meglumine adenosine cyclophosphate injection as add - on treatment of acute brenchiolitis in infants, has a good efficacy and no sefiou s side - effects. The careful observation and nursing is one of the key of successful treatment.