国产雷帕霉素洗脱支架在急性心肌梗死急诊介入治疗中的临床应用

Clinic Application of Dometic Produced Rapamycin Eluting Steut Implanting in Patient with Acote Myocardial Ifarction Receiving Ewergeucy Pdvcataueous Corouary Intervention

目的：探讨国产雷帕霉素洗脱支架（ParmerTM）在急性心肌梗死急诊介入治疗中应用的安全性及有效性。方法：选择2005年11月至2006年6月的AMI患者56例，所有患者均于发病12h内行急诊PCI治疗，分析即刻疗效和随诊结果。结果：56例患者急诊介入治疗均获得成功。共置入58枚PartnerTM。术中发生慢血流3例，住院期间未发生有关的严重并发症。2～7（4±2）月随访期内，3例患者因再次胸痛入院，其中2例经冠脉造影证实为其他冠脉分支新病变，1例为支架内再狭窄，行再次介入治疗，其余患者随访期内未出现心脏事件。56例患者中共6例复查了冠状动脉造影，ParmerTM支架内无再狭窄。结论：国产雷帕霉素洗脱支架（PartnerTM）在急性心肌梗死的急诊介入治疗中安全有效。

Objective：AIM：To investigate safety and efficacy of domestic produced rapamycin eluting stent（PartnerTM）implanting in patient with acute myocardial infarction（AMI） receiving emergency percutaneous coronary intervention. Methods： From November. 2005 to June. 2006, a total of fifty-six patients with acute myocardial infarction received emergency PCI within twelve hours from the beginning of the heart attack. The immediate angiographic detection and clinic follow-up were performed in all 56 patients. Results. Fifty-six lesions of fifty-six patients were treated and fifty-eight Partner TM stents were successfully implanted. Three cases had slow-flow in culprit lesions during operation. No serious complications were found in hospital. Clinical follow- up of fifty-six patients were conducted for 4±2months.There were no cardiac events except for three patients having angina pectoris. Repeat coronary angiography was done in three patients, two of them developed new lesions in other coronary artery and one showed restenosis in stents （PartnerTM）. The restenosis case received PCI again. Repeat angiography was performed at six of fifty-six patients no restenosis occurred in all PartnerTM stents. Conclusion：PartnerTM stent is safe and effective in the treatment of AMI.