期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

低排泄型高尿酸血症相关候选基因研究进展 被引量：1

Advances in the Study of the Candidate Genes Correlated with Under-excretion Type Hyperuricemia
下载PDF
导出
摘要 低排泄型高尿酸血症指24小时尿酸排泄少于600mg,属于多基因遗传缺陷型。现就目前有关尿酸清除降低相关候选基因:尿酸转运蛋白基因、leptin基因、ApoE基因、尿调素基因作一综述。 Under-excretion type hyperuricemia denotes the mean excretion of uric acid under 600mg/ 24h. It is a polygenic inheritance defect . This article introduces some candidate genes associated with the hyperuricemia, such as urate transporter/channel,leptin gene,ApoE gene and UMOD gene.
作者 孙玉萍 姚华
机构地区 新疆医科大学基础医学院 新疆医科大学公共卫生学院
出处 《国际遗传学杂志》 CAS 2006年第5期397-400,共4页 International Journal of Genetics
关键词 高尿酸血症 低排泄型 候选基因 Hyperuricemia Under-excretion type Candidate gene
分类号 R589.7 [医药卫生—内分泌]
  • 相关文献

参考文献24

  • 1Leal-Pinto E,Cohen BE,Abramson RE.Functional analysis and molecular modeling of a cloned urate transporter/channel.J Membr Biol,1999,169:13-27.
  • 2Lipkowitz MS,Leal-Pinto E,Rappoport JZ,et al.Functional reconstitution,membrane targeting,genomic structure,and chromosomal localization of a human urate transporter.J Clin Invest,2001,107:1103-1115.
  • 3Tureci O,Schmitt H,Fadle N,et al.Molecular definition of a novel human galectin which is immunogenic in patients with Hodgkin's disease.J Biol Chem.1997,272:6416-6422.
  • 4Enmoto A,Kimura H,Chairoughdua A,et al.Molecular identification of a renal urate anion exchanger that regulates blood urate levels.Nature,2002,417:447-452.
  • 5Enomoto A,Niwa T,Kanai Y,et al.Urate transporter and renal hypouricemia.Rinsho Byori,2003,51:892-897.
  • 6Habu Y,Yano I,Okuda M,et al.Restored expression and activity of organic ion transporters rOAT1,rOAT3 and rOCT2 after hyperuricemia in the rat kidney.Biochem Pharmacol,2005,69:993-999.
  • 7Ghio AJ,Ford ES,Kennedy TP,et al.The association between serum ferritin and uric acid in humans.Free Radic Res,2005,39:337-342.
  • 8Yokode M,Kita T.Aging and Oxidative Stress.JMAJ 2002,45:277-282.
  • 9Wu X,Muzny DM,Lee CC,et al.Two independent mutational events in the loss of urate oxidase during hominoid evolution.J Mol Evol,1992,34:78-84.
  • 10Nagahama K,Iseki K,Inoue T,et al.Hyperuricemia and cardiovascular risk factor clustering in a screened cohort in Okinawa,Japan.Hypertens Res,2004,27:227-233.

二级参考文献25

  • 1Ahima RS et al. Nature, 1996, 382: 250-252.
  • 2Chehab FF et al.Genet, 1996,12: 318-320.
  • 3Vogel G. Science, 1996, 274; 1466-1467.
  • 4Sabogal JC. Obstet Gynecol Surv, 2001, 56: 225-230.
  • 5Graham M et al. Nature, 1998, 394: 897-901.
  • 6Sierra-Honigmann MR et al. Science, 1998, 281: 897-901.
  • 7Han DC et al. Kidney Int, 2001, 59: 1315-1323.
  • 8Caro JF et al .Diabetes, 1996, 45: 1455-1462.
  • 9Arcuri P et al. Int J Mol Med, 2000, 6: 97-99.
  • 10Truett GE et al. Genetics,1991, 88: 7806-7809.

共引文献4

同被引文献19

  • 1刘爱华,黄慈波.原发性高尿酸血症与痛风代谢相关基因研究进展[J].中国临床保健杂志,2004,7(5):395-398. 被引量：3
  • 2陈颖,苗志敏,李长贵.原发性高尿酸血症和痛风分子遗传学研究进展[J].国际内分泌代谢杂志,2006,26(3):184-186. 被引量：10
  • 3Nyhan W L. Inherited hypemricemic disorders [J].Contrib Nephrol,2005,147:22 - 34.
  • 4Garcia-Pavia P, Tortes R J, Rivero M, et al. Phosphoribosylpyrophosphate synthetase overactivity as a cause of uric acid overproduction in a young woman[J]. Arih Rheum ,2003,48 ( 7 ) :2036 - 41.
  • 5Albertini R J, Nicklas J A,O'Neill J P,et al. In rico somatic mutation in humans : measurement and analvsis[J].Annu Rec Genet, 1990,24:305 - 26.
  • 6Grcgoric A,Rabelink G M, Vokac N K,et al. Eighlcen-year follow-up of a patienl with partial hypoxanthine phosphoribosyltrmasferase deficiency and a new mutation[J]. Pediatr Nephrol,2005,20 : 1346 - 8.
  • 7Yamada Y, Nomura N, Yamada K, et al. Molecular analysis of HPRT deficencies:An update of the spectrum of Asian mutations with novel mutations [ J ]. Mol Gene Metab,2007,gO : 70 - 6.
  • 8Fischer H,Eshjornsson M,Sabina R L,et al. AMP deaminase deficiency is associated with lower sprint cycling performance in healthy subjects[J].J Appl Physiol,2007,103 : 3 5 - 22.
  • 9Levartovsky D, Lagziel A, Sperling O, et al. XDH gent mutation is the underlying cause of classical xanthinuria : a second report [ J ]. Kidney Int, 2000,57 : 2215 - 20.
  • 10Ichida K, Matsumura T, Sakuma R, et al. Mutation of human molybdenum cofactor sulfurase gent is responsible for classical xanthinuria type Ⅱ[J]. Biochem Biophys Res Commun ,2001,282 : 1194 - 200.

引证文献1

二级引证文献24

国际遗传学杂志
2006年 第5期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部