两种方案治疗小儿癫痫的成本-效用比较

Cost-utility Analysis of Two Therapeutic Schemes for Epileptic Children

目的评价两种治疗小儿癫痫的方案的疗效和经济性,探索成本-效用方法的应用。方法对63例小儿癫痫患者分为两组(A:门诊随访组,B:住院治疗组),使用自编小儿癫痫生命质量量变表对患者进行评价,提取评分法获得效用值,进行成本-效用分析。结果B组的成本-效用比(CUR)为32169.49元/QALY,A组的CUR值为38350.15元/QALY,敏感度分析得到一致结果,增量成本效用分析表明每增加1QALY,A组至少需追加花费23892.69元,故认为B方案在一定条件下更为经济、有效。结论对于慢性病患者采用CUA分析,能够全面评价患者生命质量,保证卫生资源的合理利用。

OBJECTIVE To evaluate the economic effectiveness in different therapeutic schemes for the treatment of children with epilepsy,and explore the methodological of cost-utility analysis（CUA）. METHODS 63children with epilepsy were seleted prospectively,These patients were divided into two groups which received different therapeutic schemes （A ：ambulatory follow-up treatment group,B：hospitalizcaion group）. Quality of life （QOL）were measured with self-administered instrument of epilepsy. Utility scores were obtained so as to conduct CUA. RESULTS after 120 day＇s follow-up,average cost per quality-adjusted life year（QALY）for group B was 32169.49 yuan （RMB）, and group A was 38350. 15 yuan （RMB） respectively. Sensitivity analysis also were similar results. Incremental cost analyisis show that extra cost per QALY gained by group A was 23892.69 yuan （RMB）. CONCLUSION Base on this study,B scheme may be cost-saving for children with epilepsy. CUA is a valuable source of information which has resource implications for the health services.