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口服渗透泵控释制剂的工艺研究发展 被引量：1

Development of Osmotically Controlled Oral Drug Delivery System
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摘要 渗透泵控释制剂有很好的发展前景,但目前的研究还很有限。通过查阅文献,本文对口服渗透泵制剂的工艺进行了一些总结,以渗透泵制剂的发展、渗透泵制剂的片芯前处理、渗透泵的包衣与致孔、渗透泵的不同类型制备方法为体系希望加以阐述。 Osmotical controlled oral drug delivery system has its glorious prosperous. By referring to the previous articles, the author attempts throw some light on its development, with the different sections： the development, preparation, coating, percolating.
作者 周伟利 寇翔
机构地区 浙江绍兴第二医院 沈阳药科大学
出处 《海峡药学》 2006年第5期192-195,共4页 Strait Pharmaceutical Journal
关键词 渗透泵 口服渗透泵 工艺 Osmotieal Oral Deliver system
分类号 R94 [医药卫生—药剂学]
  • 相关文献

参考文献33

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  • 2ZiaV,RajewskiRA,BornanciniER,etal.Effect of alkyl chain length and degree of substitution on the Complexation of sulfoalkyl ether-βcyclodextrin with steroids[J].J Pharm Sci,1997,86(2):220-224.
  • 3Okimoto K,Rajewski RA,Stella VJ,etc al.Release of testosterone from an osmotic pump tablet utilizing (SBE)7m-β-CD as both a solubilizing and an osmotic pump anent[J]J Controlled Release,1999,58(1):29～38.
  • 4Okimoto K,Miyake M,Ohnishi N,etc al.Design and evaluation of an osmotic pump tablet(OPT) for predisolone,a poorly water soluble drug,using (SBE)7m-β-CD[J].Pharm Res,1998,15(10):1562～1568.
  • 5Okimoto K,Ohike A,Ibuke R,etc al.Design and evaluation of an osmotic pump tablet(OPT)forChlorpromazine using (SBE)7m-β-CD[J].PharmRes,1999,16(4):549～554.
  • 6Okimoto K,Ohike A,Ibuke R,etc al.Factors affecting membrane controlled drug release for an osmotictable(OPT),utilizing (SBE)7m-β-CD as both a solubilizer and osmotic agent[J].J ControlledRelease,1999,60(2-3):311～319.
  • 7ModiNB.,Lindemulder B.,Gupta SK.Single-and multiple -dose pharmacokinetics of an oral once -a-day osmotic controlled -release OROS (methylphenidate HCl) formulation[J].J Clin Pharmacol,2000,40(4):379～388.
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二级参考文献6

  • 1罗卓雅,林华庆.口服缓/控释制剂的体外释放度试验概述[J].中国药品标准,2000,1(3):9-12. 被引量：1
  • 2Zentner GM,Mcclelland GA,Sutton SC.Controlled porosity-and resin-modulated osmotic drug delivery systems for release of diltiazem hydrochloride [J].J Controlled Release,1991,16(1):237-244.
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  • 4Wang XZ.Study on natural polysaccharide macromolecular polymers used as excipients in osmotic pump and other controlled release preparations [A].Doctor Graduate Thesis of Shanghai Medical University [C].Shanghai:Shanghai Med Univ,1992.
  • 5Liu L,Khang G,Rhee JM,et al.Monolithic osmotic tablet system for nifedipine delivery [J].J Controlled Release,2000,67(2-3):309-322.
  • 6姬静,郭圣荣,方晓玲.乙基纤维素在药物制剂中的应用[J].中国医药工业杂志,2000,31(2):89-92. 被引量：24

共引文献20

同被引文献12

引证文献1

二级引证文献8

海峡药学
2006年 第5期

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