不同产地五味子果实中甲素和乙素的差异性

Deoxyschizandrin and schisandrin B contents of Schisandra chinesis fruit from different origins

研究五味子果实中的甲素和乙素含量是否存在产地间差异,分析其影响因素,为中草药生产、加工企业选择五味子果实药效显著、品质优良的产地提供依据。收集了16个产地的五味子果实,采用高效液相色谱仪分别测定五味子甲素、乙素含量。结果表明,五味子甲素、乙素含量在产地间差异显著,二者含量最高的产地分别是最低产地的2.14倍和3.3倍。将各产地的五味子甲素、乙素含量与原产地的地理气候因子进行相关分析表明,甲素含量与主要气候因子中的温度、湿度呈显著正相关关系;乙素与温湿度相关不显著。根据主要药效成分含量,初步选择黑龙江省的苇河、吉林省的柳河为五味子品质优良产地。

To provide valuable reference for selecting optimal origin of Chinese herbal medicine, Schisandra chinensis fruits were collected from 16 origins, and their deoxyschizandrin and schisandrin B contents were analyzed by HPLC. The results indicated that there exited significant differences in deoxyschizandrin and schisandrin B contents among different origins, with the highest contents being 2.14 and 3.3 times as high as those of the lowest, respectively. The deoxyschizandrin content had a significant positive correlation with temperature and humidity, while schisandrin B content didn＇t. The Weihe County in Heilongiiang Province and Liuhe County in Jilin Province were tentatively selected as the optimal origins of S. chinensis fruit based on the contents of main medicaments.