应用水螅细胞重聚体对2神食品添加剂安全性评价的探讨

Using Hydra Reaggregations Evaluating the Safety of Two Kinds of Food Additives

应用水螅细胞重聚体对苯甲酸钠、亚硝酸钠２种食品添加剂的安全性进行了研究．结果表明，苯甲酸钠、亚硝酸钠对水螅重聚体的生长发育均产生抑制作用，抑制的起始浓度分别为：３４．７Ｘ１０（－４）ｍｏｌ／Ｌ、２．９×１０（－３）ｍｏｌ／Ｌ。并且细胞重聚体的解离时间与受试物浓度呈负相关趋势。因此，水螅细胞重聚体技术可以作为预测食品添加剂潜在毒性的快速筛选的一种方法．

his paper studied the safety of two kinds of food additives using Hydra reaggregations. The results showed that both sodium benzoate and sodium nitrite inhibited the growth of reaggregations. The minimum effective concentrations were 34. 7 X 10-4 mol/L and 2. 9 X 10-3 mol/L respectively. In addition, the negative correlation existed between the depolymerization time of the reaggregations and the concentration of food additives. Therefore, Hydra reaggregations technique will be a rapid screening method for predicting the potential toxicity of food additlves.