我院2002年～2005年311例药品不良反应报告分析

Analysis on 311 Cases of Adverse Drug Reaction Report in Our Hospital during 2002～2005

目的：了解我院药品不良反应（ADR）的发生特点及评价ADR报告填写质量，促进临床合理用药。方法：制作Excel表，对2002年～2005年收集到的311例ADR根据患者性别、年龄及药品种类、ADR临床表现等分类，并进行统计分析。结果：由抗菌药物导致的ADR所占比例最高；皮肤及其附件损害的ADR约为总报告例次的50％；ADR报告总数偏少。结论：应加强专业人员的业务和素质培养，合理使用抗菌药物，以减少和避免ADR的发生。

OBJECTIVE： To investigate the features of adverse drug reaction（ADR） in our hospital and evaluate the quality of ADR report in order to promote rational clinical drug use and find out the existing problems in the report. METHODS： Microsoft Excel was designed to analyze statistically the sex and age of the patients, category of the used drugs and the clinical manifestations of ADR in 311 cases of ADR report collected between 2002 and 2005. RESULTS： The occurrence of ADR induced by antibacterials ranked the first. ADR affecting skin and its appendages counted for 50% of the total. The numbers of ADR reports were found to be less than expected. CONCLUSIONS： Professional staff training should be strengthened,the use of antibacterials should be rationalized to lessen and avoid the occurrence of ADR.