摘要
微RNA(miRNA)是一类非编码单链小分子RNA,在转录后水平调节基因的表达。最新研究发现miRNA与人类肿瘤密切相关,甚至有人认为某些miRNA就是肿瘤基因或肿瘤相关基因。现综述miRNA与人类肿瘤发生、发展、诊断、治疗和预后的研究进展。
MicroRNAs (miRNAs) are small non-coding RNA molecules that post-transcriptionally regulate gene expression. Advanced studies show that miRNA are involved in cancer. Even some scientists regard miRNAs as oncogenes or tumor associated genes. This review tries to have a brief introduction on the progress in the relationship between miRNAs and tumor's formation,development, diagnosis,therapy and prognosis in humans.
出处
《国际肿瘤学杂志》
CAS
2006年第10期731-733,共3页
Journal of International Oncology
关键词
微RNA
肿瘤
癌基因
MicroRNAs
Neoplasms
Oncogenes