恶性骨肿瘤的保肢治疗

Clinical analysis of the treatment of reserving limb for patients with malignant bone tumor

目的：探讨肢体恶性骨肿瘤保肢治疗的疗效。方法：对40例肢体恶性骨肿瘤患者行保肢治疗。患者术前均进行新辅助化学治疗。肿瘤切除后分别采用人工假体置换、瘤段灭活再植及同种异体骨关节移植等方法行保肢治疗。结果：40例患者均获随访，随访时间4—82（平均34．8）个月。术后8例发生并发症。参照Ennecking术后功能评定标准进行功能评估，优良率为72．5％。结论：保肢手术是治疗肢体恶性骨肿瘤的较理想方法，恰当的手术方法及新辅助化学治疗可延长了患者的生命，提高患者的生活质量。

Objective To investigate the curative effect of the treatment of reserving limb for patients with malignant bone tumor. Methods Forty patients with bone neoplasms underwent the operation of reserving limbs. The neoadjuvant chemotherapy was given to all the patients before the operation. After the ablation of the tumor we used the artificial prosthetic replacement, tumor tissue deactivation and reimplant, variant bone and joint transplantation to reserve the limb. Results All the patients were followed up. The average follow-up time was 34.8 months. Eight patients got complications. And the fineness rate was 72.5 % according to functional evaluation standard of Enneking after surgical treatment of bone tumor. Conclusion The operation of reserving limb was an ideal method to cure the malignant bone tumor. The proper operative treatment with neoadjuvant chemotherapy is helpful to extend the life of the patients and increase the quality of life.