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64层螺旋CT心肌早期低灌注改变诊断心肌梗死——与SPECT的对比研究 被引量:8

Early low contrast enhancement in diagnosis of myocardial infarction with 64-slice spiral CT:comparison with SPECT
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摘要 目的对比较核素心肌灌注检查结果,评价后心电门控的64层螺旋CT早期低灌注改变诊断心肌梗死的价值。方法以SPECT结果为标准,将10位患者的188段心肌分为5组(正常组,灌注轻度减淡组,灌注中度减淡组,灌注重度减淡组和灌注缺损组),对不同分组的心肌CT值进行统计学分析。采用受试者操作特性ROC曲线获取心肌低灌注改变诊断心肌梗死的最佳阈值。结果正常组心肌CT值与梗死各组心肌CT值之间有显著差异(P<0.01)。以65Hu作为诊断心肌梗死的阈值,CT诊断的敏感性为91.8%,特异性为79.9%。结论64层螺旋CT早期低灌注改变可以准确地诊断心肌梗死改变,并可进行定量分析。 Objective To assess the diagnostic value of contrast enhanced CT with retrospectively ECG-gating in the detection of myocardial infarction, comparison with the results of single photon emission computed tomography (SPECT). Methods 188 segments myocardium of 10 patients were studied with contrast-enhanced retrospectively ECG-gated CT. Reformatted short-axis images were assessed for myocardial perfusion deficits. Perfusion deficits were compared with the score of SPECT by using one-way ANOVA analysis and ROC analysis of variance. Results There was significant difference between infracted myocardium and normal myocardium at CT attenuation (P〈0.01). Regarding 65 Hu as the diagnostic standard of myocardial infarction, the sensitivity was 91.8%, the specificity was 79.9%. Conclusion The changes of early low contrast enhancement permit the detection and quantitatively characterization of myocardial infarction.
出处 《中国医学影像技术》 CSCD 北大核心 2006年第10期1460-1463,共4页 Chinese Journal of Medical Imaging Technology
关键词 体层摄影术 X线计算机 单光子发射型计算机断层摄影术 心肌梗死 Tomography, X-ray computed Single photon emission computed tomography Myocardial infarction
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参考文献8

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