中西医结合治疗高催乳素血症临床研究

Clinical study on hyperprolactinemia With Combinationtreatment of TCM and Western Medicine

目的:前瞻性研究中西结合治疗高催乳素血症的临床疗效。方法将2004年1月～2006年2月我院妇科门诊95例高催乳素患者进行随机分组,中西药组56例,采用中西医结合疗法,即溴隐亭加中医辩证治疗;西药组39例,单纯给予溴隐亭治疗,对比分析两组治疗结果。结果中西药组治愈率73.21%,总有效率91.07%,反跳率0.00%,复发率31.37%;西药组治愈率51.28%,总有效率82.05%,反跳率15.63%,复发率68.75%。两组治愈率、总有效率、反跳率和复发率比较,结果分别为P<0.05、P>0.05、P<0.05和P<0.01。结论中西医结合疗法和单纯西药治疗对高催乳素血症的总有效率相近,但中西医结合疗法可提高治愈率,明显减少停药后的复发和反跳。

Objective： To Prospectively study the clinical effects on hyperprolactinemia With Combination treatment of TCM and Western Medicine. Methods 95 cases diagnosed hyperproiactinemia in gynaecology department from January 2004 to February 2006 were randomly divided into two groups： TCM and western medicine therapy group（56 cases）, in which the patients were treated by combination of TCM and western medicine, i.e. treatment with Bromocriptine （BRC） and Chinese treatment determination based on syndrome differentiation, and western medicine therapy group（39 cases）, in which the patients were treated only with BRC. The therapeutic effect of the two groups was compared. Result In TCM and western medicine therapy group the cue rate is 73.21%, the total effective rate is 91.07%, the breakthrough rate is 0.00% and the recurrence rate is 31.37%, while in western medicine therapy group it is 51.28%, 82.05%, 15.63% and 68.75% respectively. Compare the cue rate, the total effective rate, the breakthrough rate and the recurrence rate between the two groups, the result is P〈0.05, P〉0.05,P〈0.05 and P〈0.01 respectively. Conclusion the total effective rate of the treatment combination with TCM and western medicine and the treatment only with western medicine is similar, but treatment combination with TCM and western medicine can increase the cure rate, and decrease the recurrence rate and breakthrough rate significantly.