肺癌患者BALF中免疫成分的研究

Study on the Ommunologic Contents in Broncho-Alveolar Lavage Fluidfrom Patients With Lung Cancer

本研究检测了１４例肺癌患者ＢＡＬＦ中的免疫成分，并同非癌性肺病患者和正常对照者进行了比较。结果表明肺癌组ＢＡＬＦ中巨噬细胞十分显著地低于两对照组，中性粒细胞十分显著地高于两对照组，而且肺癌组ＢＡＬＦ中ＩｇＧ、ＩｇＡ、Ｃ３、Ｃ４、α１－ＡＴ、α２－ＭＧ均明显高于正常组。这些成分的改变可能反映肺瘤患者的肺局部免疫状态，提示检测这些指标有助于肺癌的早期诊断。

The immunologic contents were detected in BALF from 14 Iung cancer patients, 13 non-cancer puiminary patients and 10 mormal volunteers. The BALF of the lung cancer group was significantly lower than that of the non-cancer pulmonary diserse group or the normal control group, and the percentage of neutrophil in BALF of the lung cancer group was sigmificantly higher than that of the other two control groups. In addition, the levels of IgG, IgA,C3,C4,X1-AT and X2MG in BALF of the lung cancer group were signficantly higher than those of the normal control group. The changcs of the contcnts in lungs of the patients with lung cancer. It is helpful for earlier diagnosing lung cancer to detect those immunologic inedxes.