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2型糖尿病患者血清可溶性细胞间黏附分子与大血管病变的相关性研究 被引量：5

The relationship between serum soluble intercellular adhesion molecule-1 and diabetic macrovascular diseases
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摘要 本研究显示2型糖尿病(T2DM)大血管病变组血清可溶性细胞间黏附分子(sICAM-1)显著高于非大血管病变组和对照组,sICAM-1与hsC-RP、Fib、TG、TC以及LDL-C呈显著正相关,且SBP、hsC-RP和sICAM-1对T2DM大血管病变呈独立正相关影响。 The results in this study showed that serum sICAM-1 was significantly higher in diabetic macroangiopathic group （n= 39） as compared with non- macroangiopathic group（n= 31） and control group（n= 35）. Serum sICAM-1 was positively correlated with hsC-RP,Fib, TG, TC and LDL-C. SBP, hsC-RP and sICAM-1 were independently and significantly associated with diabetic macrovascular diseases.
作者 刘松平 张宏 谢云 赵伟 卫丽君 郑凝 方佩华
机构地区 天津医科大学代谢病医院 天津医科大学总医院核医学科
出处 《中国糖尿病杂志》 CAS CSCD 北大核心 2006年第5期359-360,共2页 Chinese Journal of Diabetes
关键词 糖尿病 2型 可溶性细胞间粘附分子-1 病变 大血管 Diabetes mellitus,type 2 Soluble intercellular adhesion molecule-1 Diseases, great vessels
分类号 R587.2 [医药卫生—内分泌]
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  • 1刘永忠,张玲.可溶性细胞间粘附分子－1及其临床意义[J].国外医学（免疫学分册）,1995,18(5):239-242. 被引量：23
  • 2Schmidt MI, Duncan BB, Scharrct AR, et al. Markers of inflammation and prediction of diabetes mellitus in adults (Atherosclerosis Risk in Communities study): a cohort study. Lancet, 1999,353:1649-1652.
  • 3Barzilay JI, Abraham L, Heckbert SR, et al. The relation of markers of inflammation to the development of glucose disorders in the elderly: the Cardiovascular Health Study. Diabetes, 2001,50:2384-2389.
  • 4Pradhan AD, Manson JE, Rifai N, et al. C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus. JAMA, 2001,286:327-334.
  • 5Festa A, Ralph BD, Russell PT, et al. Elevated levels of acute phase proteins and plasminogen activator inhibitor-1 (PAI-1) predict the development of type 2 diabetes mellitus: the insulin resistance atherosclerosis study (IRAS). Diabetes, 2000,49(Suppl 1):A24-A25.
  • 6Duncan BB, Schmidt MI, Offenbacher S, et al. Factor Ⅷ and other hemostasis variables are related to incident diabetes in adults. Diabetes care, 1999,22:767-772.
  • 7Lindsay RS, Krakoff J, Hanson RL, et al. Gamma globulin levels predict type 2 diabetes in the Pima Indian population. Diabetes, 2001,50:1598-1603.
  • 8Mcneely MJ, Bokyko EJ, Weigle DS, et al. Association between baseline plasma leptin levels and subsequent development of diabetes in Japanese Americans. Diabetes Care, 1999,22:65-70.
  • 9Yuan M, Konstantopoulos N, Lee J, et al. Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of IKKbeta. Science, 2001,293:1673-1677.
  • 10Hundal RS, Petersen KF, Mayerson AB, et al. Mechanism by which high-dose aspirin improves glucose metabolism in type 2 diabetes. J Clin Invest, 2002,109:1321-1326.

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中国糖尿病杂志
2006年 第5期

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