光学纯7,7'-二取代联二萘酚催化乙基锌对醛的对映选择性加成

Optically Pure 7,7'-Disubstituted Binaphthols Catalyzed Enantioselective Addition of Diethylzinc to Aldehydes

合成了一类光学纯的7,7’-二取代联二萘酚,并将其用在乙基锌对醛的对映选择性加成,以54％-88％的产率和最高88％的对映选择性得到了光学活性的1-苯基-1-丙醇．

Optically pure 7,7＇-disubstituted binaphthols were synthesized and used in the enantioselective addition of diethyl zinc to aldehydes to afford the corresponding alcohols with 54%-88% yields and up to 88% ee.